Cardiac Contractility Modulation (CCM) is a unique and innovative method for treating patients with moderate-to-severe Chronic Heart Failure (CHF) that are symptomatic despite optimal medical therapy. CCM signals are unique electrical pulses delivered by the Optimizer III implantable device during a special period of the heart cycle (the absolute refractory period or the period just after the heart’s excitation). Research has shown that CCM signals significantly improve the heart’s contractility by modifying the function and expression of certain proteins in the heart muscle and, through that, the function of the heart. In fact, CCM is the only treatment that actually trains the heart.
Clinical trials have shown that chronic CCM treatment is safe and significantly improves exercise tolerance and quality of life in symptomatic heart failure patients with normal QRS duration.
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From our blog
- July 2012 Meet us at the European Society of Cardiology Annual Congress, Munich, August 2012
- May 2012 Cardiostim 2012 June 13-16, 2012
- April 2012 German Society of Cardiology (DGK) Congress, Mannheim
- April 2012 Not All Heart Failure Patients Benefit from CRT
- April 2012 New article published in the Int. J. of Cardiology compares LV reverse remodeling induced by CCM and CRT