CCM Therapy delivers non-excitatory electrical pulses to the heart and is indicated for adult patients with CHF resulting from left ventricular dysfunction despite appropriate medical treatment. Now, with the Optimizer Smart, CCM can be given to CHF patients with rhythms that are not sinus. Our clinical data with earlier versions of the Optimizer, including three randomized trials, supports the efficacy and safety of CCM Therapy and the Optimizer System. CCM Therapy is mentioned in ESC 2016 guidelines for the diagnosis and treatment of acute and chronic heart failure